Malaria, an infectious disease caused by protozoan parasites from the genus Plasmodium, represents a serious global health threat.The continued emergence of drug resistant strains has severely decreased current antimalarial drug efficacy and led to a perpetual race for drug discovery.Most protozoan parasites, including Plasmodium spp., are unable t
Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells.The leucinostatin-derivative peptide ZHAWOC_6027 (peptide 6027) was tested in vitro and in vivo for activity against the intracellular apicomplexan parasite Toxoplasma gondii.While highly efficacious in vitro (EC50 = 2 nM)
Post-stroke depression significantly impairs functional recovery in patients and their quality of life.Objective: to evaluate the efficacy of vortioxetine in correcting depressive symptoms in the early recovery period of ischemic stroke, as well as its effect on the cognitive functions of patients.Patients and methods.The investigation enrolled 60
Nowadays, the Internet of Things (IoT) has become a rapid development; it can be employed by cyber threats in IoT devices.A correct system to recognize malicious attacks at IoT platforms became of major importance to minimize security threats in IoT devices.Botnet attacks have more severe and common attacks and it is threaten IoT devices.These thre
Abstract Background Gene-set analysis tools, which make use of curated sets of molecules grouped based on their shared functions, aim to identify which gene-sets are over-represented in the set of features that Swim have been associated with a given trait of interest.Such tools are frequently used in gene-centric approaches derived from RNA-sequenc